Indications for use drugs: bacterial infectious lesions of the conjunctiva, cornea, slozovoho channel, prevention of eye infections vernacular surgical interventions, removing foreign bodies, burns, chemical injuries eyes. Indications medicine: infectious eye diseases caused by susceptible pathogens (bacterial conjunctivitis, keratitis, blepharitis, trachoma). Indications medicine: infectious-inflammatory eye diseases caused by susceptible bacteria to the drug: conjunctivitis, blepharitis, purulent ulcer, keratitis, gonorrheal eye diseases in adults and infants, prevention blenoreyi newborns. The main pharmaco-therapeutic effects of drugs: an antibiotic from the group of aminoglycosides, which counteracts both gram-positive and gram-negative pathogens, shows a bactericidal action by vernacular of complex polypeptides and synthesis of ribosomes in bacteria during clinical trials demonstrated that Tobramycin is effective for superficial infections of the eye against gram-positive bacteria: Staphylococcus aureus; Staphylococcus epidermidis; Streptococcus pneumoniae, Streptococcus and other gram-negative bacteria: Acinetobacter spp; Citrobacter spp; Enterobacter spp; Escherichia coli; Haemophilus influenzae; Klebsiella pneumoniae; Moraxella spp; Proteus mirabilis; Pseudomonas aeruginosa; Serratia marcescens. Pts. The main pharmaco-therapeutic effects of drugs: antibiotics wide spectrum antimicrobial action, bacterioscopic effects which is due to inhibition of protein synthesis in cells of microorganisms, acts against most gram-positive (staphylococcus, pneumococcus, streptococcus) and gram (meninho-gonococci, escherichia, salmonella, shigell, enterobacteria) of bacteria diseases. 0,3% fl.-kr. Contraindications to the use of drugs: individual sensitivity to the drug, mycobacterial infections eye condition after removal of corneal chuzheridnoho body, the auditory nerve neuritis. Dosing and Administration of drugs: in writing a number of Intracerebral Hemorrhage - 0,3 g for the lower or upper eyelid 3 r / day, with trachoma - 4 - 5 p / day, duration of treatment depends on the severity and course of disease and the average time is 1 5 - 2 months, the treatment of trachoma - up to 4 months. vernacular group: S01AB04 - agents used in ophthalmology. Preparations of drugs: krap.och. Pharmacotherapeutic group: S01AA17 - tools vernacular are used in ophthalmology. 5 ml. milligram main pharmaco-therapeutic effects of drugs: a bacteriostatic effect on gram-positive and gram-negative bacteria - streptococcus, pneumococcus, gonococcus, Escherichia coli, Chlamydia, actinomycetes, the mechanism vernacular drug action is due to competitive antagonism with paraaminobenzoynoyu acid (PABA) and competitive inhibition dyhidropteroatsyntetazy that leads vernacular the violation of synthesis tetrahidrofoliyevoyi acids required for vernacular of purine and pyrimidine bases, Electromyography disturbed synthesis of nucleic acids (DNA and RNA) bacterial cells and inhibited reproduction. Contraindications to the use of drugs: hypersensitivity to the drug, children under 5 years. By activity, they are Both eyes (Latin: Oculi Uterque) inferior to antibiotics, but more effective against gram-positive and gram-negative cocci, Escherichia coli, shigell, klostrydiy, some simpler and others. Antibiotics. Contraindications to the use of drugs: age to 8 years. 5 ml, ophthalmic ointment 0.3% to 5 g tubes. Side effects and complications in the use of drugs: irritation, redness, itching, peeling skin. AB-sulfanilamides activity is reduced when a large quantity of purulent discharge, ie in the presence of high concentrations paraaminobenzoynoyi acid.
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