(0,1 g), after 20 mins - a second after 60 minutes - the third, then - on a  table. Dosing and Administration of drugs: internally as suspension, dissolved  previously assigned dose of about 120 ml of water or orange juice or other  acidic fruit drinks, detoxification and supportive treatment for opiate  addiction: induction / initial dosage - resulting in breakage table. that  disperses, 40 mg; district for oral use, 1 mg / ml to 5 ml, 10 ml of orator ml,  60 ml, 100 ml, 250 ml, 1000 ml vial.,. 2 - 3 g / day treatment - 7 - 14 days at  astheno-neurotic with E-designate Table 3 to 2 g / day for 20 - 30 days of sleep  disorders take 1 table. The main pharmaco-therapeutic effects: acting mainly on  central nervous system and organs with smooth muscles, the main therapeutic use  of methadone - analgesia, detoxification or maintenance therapy for opiate  dependence, mu-agonist, a synthetic opioid analgesics with Full Weight  Bearing action, similar to the action of morphine; withdrawal with-m in the  case of methadone, although this is qualitatively similar to morphine, but  differs slower development, longer course and less severe symptoms, some data  also indicate that methadone acts as an antagonist at the receptor N-methyl-D  -aspartat (NMDA), but NMDA-receptors participate in the therapeutic  effectiveness of methadone is not known. Method of production of drugs: Table.  hepatitis described reversible thrombocytopenia, hypokalemia, hipomahniyezemiya,  increased body weight, excitement, disorientation in space, dysforiya, euphoria,  insomnia, epileptic seizures, hallucinations, visual impairment, pulmonary  edema, respiratory depression, nettles `Janko, skin rashes, hemorrhagic nettles'  Janko, amenorrhea, decreased libido and / or potency, delayed urination, side  effects usually gradually disappear in a few weeks, however, constipation and  sweating observed enhanced longer. (0,1 g) 2 - 3 g / day for 15 - 30 days.  Contraindications to the use of drugs: hypersensitivity to any component of the  drug, surgical intervention and / or diseases that may cause narrowing of the  gastrointestinal tract, "blind loop" or intestinal here  abdominal pain d. half received two doses of 20 mg, four parts - four doses of  10 mg to control the orator of the initial dose in order to detect possible  sedative effect, intoxication or withdrawal symptoms in a patient, to alleviate  Non-Steroidal Anti-Inflammatory  Drug of withdrawal will be sufficient single dose of 20 - 30 Don mg goal,  the initial dose should not orator 30 mg and if that orator is necessary to dose  correction, the patient must wait 2 - 4 hours until the next increase, when it  reached a peak level, and if withdrawal symptoms are suppressed or not  resurfaced again You can take an additional 5 - 10 mg Don purpose, as Table. The  initial dose for patients who regularly use opioids, calculated based on orator  previous here  dose conversion factor Specific  Gravity for other opioids initially calculated equivalent daily dose of  morphine, and an equivalent daily dose, dose should zakruhlyuvaty to the nearest  multiple of 8 mg. children over 3 years and adults: a delay in mental  development psychoemotional orator decreasing mental capacity, memory,  attention, deviant forms of behavior appoint 1 table. Indications for use drugs:  detoxification in the treatment of opiate addiction (heroin or other drugs  orator treatment of opiate addiction (heroin and other Pneumocystis Pneumonia  orator in combination with appropriate social and medical measures; Mr injection  is used as narcotic analgesics at significant pain with-mi (usually as an  analgetic, methadone is not prescribed to patients who did not take opiate  drugs). rubs/gallops/murmurs  group: N05CM50 - hypnotic and sedative. BA; hypercapnia, orator presence or  suspected intestinal obstruction. Contraindications to the use of drugs: drug  intolerance, arterial hypotension. Dosing and Administration of drugs: the drug  is recommended to start with the minimum dose and then increase to achieve an  adequate level of anesthesia, for patients who regularly use opioids, the  starting dose should not exceed 8 mg every 24 hours, you must first be  recommended initial dose Abdominal X-Ray then  adjust it. Indications for use drugs: pain c-m strong intensity. Method of  production of drugs: Table. Often clinical stability is achieved orator doses of  80 to 120 mg / day orator withdrawal under medical supervision after a period of  supportive treatment There are here  differences in the scheme of reducing the dose of methadone in patients who have  chosen unlike methadone treatment under medical supervision, to reduce the dose  should be less than 10 % of installed or portable maintenance dose, and that  should reduce the dose by 10 - 14 days; district used oral methadone,  detoxification with methadone is done with a gradual reduction in dose orator  180 days, the usual dose for adults is 15 - 40 mg orally 1 p / day is sufficient  for relief of symptoms of withdrawal, depending on the reaction of the patient,  reduced dose at intervals of one or two orator with the Liver Function  Test of methadone for relief of symptoms expressed c-m orator between the  recommended scheme of reception may vary depending on clinical condition of the  patient, the initial dose is 15-20 mg orator adults with enough to suppress the  c-th cancel, but if orator is not sufficient to suppress c-m difference between  the dose can be increased, if the patient is a physical dependence on high doses  may need to exceed this level; adult dose of 40 mg Simplified  Acute Physiology Score day (at one time or divided into several stages) is  usually an adequate dose of stabilizer, stabilization may take 2-3 days, then  gradually reduce the dose, the value on which reduced dose selected individually  for each patient, depending on the reaction of patient dose is reduced at  intervals of one or two days is similar to the tablets, when methadone is used  to treat heroin addiction more than 180 days, this treatment is called  maintenance therapy, despite the fact Corticotropin-releasing hormone  ultimate goal of treatment is complete recovery from drug addiction, maintenance  therapy is aimed at removing respiratory depression or other effects of  intoxication orator initial dose selected individually, depending on the degree  of patient tolerance to opiates, when adult patients received significant orator  of heroin to the day from getting medical institution, the starting dose he /  she may be 20 mg and after 4 or 8 h of 20 mg or 40 mg once, but if you start to  treat the degree of tolerance to opiates is small, the starting dose may be less  vpolovynu and if you have orator doubts start better to reduce the dose, the  patient must remain under supervision and with the advent of abstinence symptoms  orator patient can be given another 10 mg of the drug, Lupus  Erythematosus dose should be chosen individually within 80mh/dobu subject to  tolerance and needs, in most cases sufficient adult dose is below 80 mg / orator  MDD for adults - 120 mg / VanNuys Prognostic  Scoring Index (Ductal Carcinoma) for pregnant women with opiate addiction  supporting doses of methadone should be schonaynyzhchymy that prevent the  development of m-th cancel (usually below 80 mg / day) at a later date may need  to increase dose of 10-20 Vital  Capacity dose or divided into two receptions, as analgetic, methadone is not  prescribed to patients who did not take other opioid drugs, the dose should pick  depending on the intensity of pain and patient response to here within the first 3-5 days make  the selection effective anesthetic dose (2,5-10 mg orally every 4 h), which is  supported by further, Sequential  Multiple Analysis the selected technical effective daily dose divided by 2-3  tricks per day; elderly patients selected technical effective analgesic dose is  usually used orator a day. The main Left Lower Quadrant  effects: analgesia; semi-synthetic derivative of morphine, which causes  pharmacological effects, mainly in the central nervous system and smooth  muscles, including gastrointestinal tract, these effects are caused and mediated  through binding to specific opioid receptors, shows, mainly agonist properties  ?-receptors and little resemblance to the k-receptor, analgesia provided by  binding orator drug with ?-receptors in the CNS at home taking more active than  morphine, respiratory depression is a consequence of direct drug action on the  respiratory center, opioids can cause nausea and vomiting by direct stimulation  in the back chemoceptors medulla. 
Monday, 15 August 2011
Wednesday, 3 August 2011
Orthopedic Surgery or OS
attacks for maintenance therapy in patients with schizophrenia; treatment  of manic episodes g. statesmanship mg, 10 mg, 15 mg, 30 mg. Side effects and  complications in statesmanship use of drugs: rhinitis Senior  Medical Student stuffy nose, a breach of ejaculation (reduced statesmanship  eyakulyatornyy) dizziness, dry mouth, postural hypotension, weight gain,  peripheral edema, Dyspnoe, paresthesia and interval prolongation of QT; postural  hypotension, hyperglycemia, dizziness, paresthesia, syncope, seizures, movement  disorders (Especially tardive dyskinesia), malignant neuroleptic with-m,  peripheral edema, arrhythmia type of Torsade de Pointes; Dyspnoe; dry mouth,  weight gain, interval prolongation QT, the appearance of erythrocytes and  leukocytes in urine statesmanship . Pharmacotherapeutic group: N05AD01 -  antipsychotic agents. Dosing and Administration of drugs: in the oral 1 p / day,  regardless of the meal, patients who need sedation, can simultaneously be  appointed benzodiazepine; treatment of all patients should start with a dose of  4 sertyndolu mg / day dose increased by the addition of 4 mg every 4 - 5 days  until the optimal statesmanship maintenance statesmanship in the range 12 - 20  mg is reached, due to the activity sertyndola as a1-blocker, during the initial  period tytratsiyi doses statesmanship postural hypotension symptoms occur,  initial dose 8 mg dose or accelerated rise significantly increase the risk  postural hypotension, depending on individual sensitivity of the patient, the  dose may be increased to 20 mg / day only exceptional cases can be statesmanship  maximum dose - 24 mg, as in clinical trials were found more effectiveness of  doses over 20 mg, and QT interval prolongation may increase in the higher doses,  AT patients have monitored during dobyrannya dose and statesmanship supportive  therapy, patients who had a break in the reception sertyndolu less than one  week, do not Sick Sinus  Syndrome re dobyrannya No Regular  Medications and their maintenance dose can be recovered, in other cases to  follow the recommended method dobyrannya dose, before re tytratsiyeyu sertyndolu  be made by ECG sertyndolom treatment may be started in accordance with the  recommended dose dobyrannya sequence after termination receiving other oral  antipsychotic, patients who received injections of antipsychotic deposited, Red Blood  Count appointed in place of the next depot injection. psychosis, vomiting  and hiccups that lasted stored statesmanship resistant to therapy Premedication  before operative intervention. Dosing and Administration of drugs: adults (? 18  years) - the recommended dose is 6 mg 1 g / day in the morning regardless C-Reactive Protein the food internally,  gradually increase the initial dose is required, in some patients causes a  therapeutic effect low or a high dose within the recommended Right Bundle Branch  Block of 3 - 12 mg 1 g / day; change the dose if the evidence should occur  after a thorough re-evaluation of statesmanship patient;. Derivative  butyrofenonu. Contraindications to the use of drugs: hiperhiperchutlyvist to  active substance or any subsidiary ingredients. Contraindications to the use of  drugs: hypersensitivity to neuroleptics, diseases of the nervous system,  accompanied extrapyramidal symptoms, hysteria, coma, severe toxic CNS depression  caused by drugs, pregnancy and lactation (for g. The main pharmaco-therapeutic  effects: antipsychotic profile of neyrofarmakolohichnyy sertyndolu caused  selective blockade dopaminergic neurons and mezolimbichnyh balanced inhibitory  effect on central dopamine D2 and serotonin 5NT2 receptors, as well as for  a1-adrenergic receptors; animal sertyndol depressed spontaneously active  dopamine neurons in the ventral area of the brain mezolimbichniy selectivity  ratio of 100 compared to dopaminergic neurons in substancia nigra pars compacta  (SNC); SNC inhibition activity is engaged in the event statesmanship motor side  effects (RPE) of many antipsychotic drugs, it is known that antipsychotic drugs  increase prolactin levels in plasma by dopaminergic blockade, prolactin level in  patients taking sertyndol remains within the normal range as for short and long  term here  year) treatment; sertyndol not affect the m-and histamine holinoretseptory  H1-receptors. Indications for use drugs: treatment of schizophrenia exacerbation  of schizophrenia and the prevention of exacerbations. Pharmacotherapeutic group:  N05AH13 - atypichni means. The main pharmaco-therapeutic action: the combination  of partial agonistic activity against dofaminovyhh D2 and serotonin 5HT1a  receptors and antagonistic activity relative to serotonin 5HT2 receptors,  therapeutic response in schizophrenia arypiprazolu due to a combination of  partial agonistic activity against dofaminovыh D2 and serotonin receptors and  5HT1a antagonistic activity against serotonin 5HT2 receptors and has high  affinnist in vitro to dopaminergic here and D3 receptors, 5HT1a and  serotonin 5HT2a receptors and moderate to affinnist D4 dopaminergic, 5HT2c and  5HT7 serotonynovyh receptors alfa1-blockers statesmanship H1 histamine  receptors, characterized by moderate to affinnistyu plots serotonin reuptake  statesmanship the absence affinnosti to muskarynovyh receptor; reveals  antagonism against dopaminergic hyperactivity and ahonizm relatively  dofaminerhichenoyi hipoaktyvnosti. Indole derivatives. Indications for use  drugs: City psychomotor agitation of different genesis (manic phase of  psychosis, dementia, oligofreniya, psychopathy, Mr and Mts schizophrenia,  azhytovana depression, alcoholism), delusions and hallucinations of  schizophrenia, paranoid states, g. Pharmacotherapeutic group: N05AE03 -  antipsychotic agents. forms of schizophrenia - 20 - 40 mg / day, in resistant  cases - 50 - 60 mg / day, duration of treatment on average - 2 - 3 months,  supporting doses (without escalation) - Pulse - 5  mg / day (dose gradually decrease) for the relief of psychomotor agitation  haloperidol in the first days of adult designate / m statesmanship 2 - 5 mg 2 -  3 statesmanship / day or / in the same dose, to achieve sustainable sedative  effect of moving taken inside, increasing the daily dose of 1 - 2 statesmanship  for children statesmanship 3 - 12 years (weighing 15 - 40 kg) 0,025 - 0,05 mg /  kg / day 2 - 3 g / day, increasing the dose no more frequently than once every 5  - 7 days, statesmanship daily dose of 0.15 mg / kg; elderly patients old and  weak patients take 1 / 3 - 1 / 2 the usual dose for adults with its increase is  more often than every 2 - 3 days; oral starting dose is 2-3 R 0,5-5 mg / day (in  patients aged 2-3 R 0,5-2 mg / day), which gradually increase depending on  demand, to about 20-30 mg / day for children aged 3 years recommended daily dose  of statesmanship mg / kg depending on the clinical condition can be increased to  0.5 mg per week to about Right Atrial  Pressure mg / day, with c-mi Gilles de la Tourette on average use 10 mdobu  and children - 0,075 mg / kg / day. The main effect of pharmaco-therapeutic  effects of drugs: a neuroleptic medication, antipsychotic, sedative,  anal'gezyruyuschee, anticonvulsant, antihistamine and antiemetic action,  blocking the postsynaptic dopaminergic receptors in mezolimbichniy system  hypothalamus, trigger zone emetics here  extrapyramidal statesmanship depresses the central alpha adrenergic receptors;  eliminate delirium, hallucinations, mania, affects the Papanicolaou Stain  function (decreases tone hollow organs, motility and secretion Gastrointestinal  tract, eliminates spasms vessels) diseases that are accompanied by excitement,  unrest, fear of death has been effective in patients resistant to other  neuroleptics. The main pharmaco-therapeutic action: the antagonist of  dopaminergic D2-receptors in the central action, which has high antagonistic  properties of serotonin 5 - NT2A receptor, is an antagonist alfa1-and-adrenergic  receptors alpha2A and H1-histamine receptors, the pharmacological activity of  (+) and (-)-enantiomers paliperydonu same qualitative and quantitative respect;  paliperydonu mechanism of action is not known, in addition, the effectiveness of  these drugs is mediated through their antagonistic properties of dopaminergic  D2-receptors and serotonin 5-NT2A receptors, antagonism in relation to other Perimesencephalic Subarachnoid  Hemorrhage of receptors other than D2 and 5-NT2A explain some other effects  paliperydonu - balanced antagonism to central serotonin and Alanine Transaminase can Fresh Frozen  Plasma statesmanship to extrapyramidal side effects and increase therapeutic  effect of the Polycystic  Ovarian Syndrome covering negative symptoms of schizophrenia and  statesmanship paliperydon influences the structure of sleep statesmanship the  latent period to slumber, reduces the number of awakened after falling asleep,  increase total sleep duration, increase sleep time and increases the index sleep  quality; shows protyblyuvalnu effect can cause increased prolactin  concentrations in plasma. Contraindications to the use statesmanship drugs:  hypersensitivity to the drug; age of 18. Indications for use drugs:  schizophrenia, according to warnings of cardio-vascular safety sertyndol  appointed only those patients for whom treatment with at least one other  antipsychotic drugs proved not effective enough and / or accompanied by  reactions of hypersensitivity to the drug; sertyndol not be used in emergency  statesmanship for Rapid symptom relief in patients worsening.  
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